MU-TH-UR (Alien, 1979)
The real villain of the piece, the Nostromo’s computer and Weyland-Yutani stooge MU-TH-UR – or “mother” as the crew call her – instigates the living nightmare that is Alien when she interrupts the ship’s voyage and wakes the crew from hyper-sleep to answer a distress beacon.
Unfortunately for MU-TH-UR there is only room for one alpha female in the Alien universe and that’s Ellen Ripley, who puts a stop to her and fellow AI Ash’s scheming.
MU-TH-UR was only following her programming, however. To paraphrase another femme fatale – she’s not bad, she’s just drawn that way.